Department of laboratory diagnosis and treatment of tuberculosis | Print |




Surkova Larisa Konstantinovna, Doctor of Medical Sciences, professor, head of the department for laboratory diagnosis and treatment of tuberculosis.


Scientific and practical directions of the department of the State Institution " Republican Scientific and Practical Centre of Pulmonology and Tuberculosis"

Scientific researches are conducted within the framework of the subprogram "Tuberculosis" of the State Program "People's Health and Demographic Security of Belarus"; 2016-2020. The scientific and practical tasks performed in the department are:

- development and implementation of new organizational and methodological approaches to laboratory diagnosis of tuberculosis and its drug-resistant forms;

- development of a national strategy for the development of microbiological diagnosis of tuberculosis and its drug-resistant forms in the Republic of Belarus for the coming years;

- development of new approaches to the organization and conduct of treatment of tuberculosis and its drug-resistant forms in the Republic of Belarus.

I scientific and practical direction - molecular genetic studies in the diagnosis of pulmonary and extrapulmonary tuberculosis and its drug-resistant forms.

II direction - analysis of mutations in the genes of mycobacterium tuberculosis, determining the drug resistance of the causative agent of tuberculosis in the Republic of Belarus. The study of the genetic variability of the causative agent of tuberculosis circulating in the territory of the Republic of Belarus, the accelerated identification of the Beijing genotype in patients. Monitoring of the Beijing genotype and its sub BO / W.

III direction - development of new algorithms for diagnostics of drug-resistant tuberculosis, mycobacteriosis and differential diagnosis of tuberculosis with the use of minimally invasive video-assisted surgical interventions.

IV direction - development and implementation of new treatment regimens for rifampicin-resistant tuberculosis (MDR / TB, XDR / TB), evaluation of the effectiveness of treatment with new drugs, monitoring the use of new medicines in the treatment of rifampicin-resistant tuberculosis, improving the treatment of tuberculosis in the Republic of Belarus, autologous multipotent mesenchymal stromal cells in the complex treatment of tuberculosis.

V direction - mycobacteriosis of the lungs, improvement of detection of nontuberculous mycobacteria, algorithm for diagnosis of mycobacteriosis, new algorithms for the treatment of mycobacteriosis of the lungs, monitoring of species diversity of nontuberculous mycobacteria in the Republic of Belarus

VI direction - new approaches to the morphological diagnosis of tuberculosis, evaluation of the use in the diagnosis of PCR "in situ", immunohistochemical studies. Study of variability of morphology and clinical and morphological phenotypes of tuberculosis.